Have you ever wondered why isolating quality DNA from Spit/Saliva is inconsistent, especially when it comes to DNA sequencing?
Spit/Saliva is a complex biological matrix with a mixture of different DNA sources that vary in percentage from one individual to another
Given this heterogeneity, It is not surprising that success or failure of this kind of sample varies widely when using spit/saliva collection devices such as liquefied spit collection tubes or foam/sponge based swabs.
In contrast, the use of standard swabs for sample collection yields far less complex gDNA; in fact over 95% comes from buccal cells, making it the most prominent single source of gDNA in this sample type. This is what iSWAB-DNA has shown time after time…iSWAB-DNA is designed to selectively lyse mammalian cells and not bacteria, resulting in the highest quality human gDNA that works every single time
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