Mawi - Biosampling Reinvented
  • OUR PRODUCTS
  • ABOUT US
    • Careers
    • Our Team
    • Our Technology
    • Worldwide Contacts
  • LEARN
    • Articles & Applications
    • DNA/RNA Extraction methods
    • Blog
    • FAQ
  • CONTACT
Request sample kit arrow

News

  • Active Partnerships
  • Press
  • Blog
    • About Mawi DNA Technolgies
    • Announcements
    • Articles & Cohort Studies
    • Biosampling Technology
    • Events
    • Hematology
    • In The Press
    • iSWAB Insights
    • News
    • Uncategorized
  • Blog
  • Articles & Cohort Studies
  • Epigenetic Differences in Inflammation Genes of Monozygotic Twins are related to Parental Emotional Availability and Health
May 26, 2020

Epigenetic Differences in Inflammation Genes of Monozygotic Twins are related to Parental Emotional Availability and Health

Abstract

The inflammatory response is an immune defense engaged immediately after injury or infection. Chronic inflammation can be deleterious for various health outcomes and is characterized by high levels of pro-inflammatory markers such as C-reactive protein (CRP), cytokines interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-α). A large body of research demonstrates these inflammatory markers are responsive to stress and quality of social relationships throughout the lifespan. For example, the quality of the early parental bond predicts various health outcomes and may be driven by changes in immune function. Epigenetic processes, such as DNA methylation, may be one mechanism by which early social experiences shape immune functioning. The present study used a monozygotic twin difference design to assess if primary caregiver emotional availability at 1 year and 2.5 years predicted immune gene methylation at 8 years of age. Further, we assessed if inflammation gene methylation was related to general health problems (e.g. infections, allergies, etc.). We found that parental emotional availability at 1 year, but not 2.5 years, was related to methylation of various immune genes in monozygotic twins. Furthermore, twin pairs discordant in health problems have more difference in immune gene methylation compared to twin pairs concordant for health problems, suggesting that methylation of immune genes may have functional consequences for general health. These results suggest that the emotional component of attachment quality during infancy contributes to immune epigenetic profiles in childhood, which may influence general health.

For more information, see the full paper here

Related news

Apr 17, 2023

Candida Data Using iSWAB In Response to New Infectious Diseases...

A deadly fungal infection, Candida Auris, is becoming a serious threat. This drug-resistant strain is deadly for those with weakened immune systems and is spreading at an alarming rate. The READ MORE

Apr 11, 2023

Top Reasons to Ditch Your Current VTM. Upgrade your Viral…...

Mawi DNA has developed iSWAB-RC-EL, an FDA approved sample collection device for transport and storage of samples suspected of containing an infectious disease*. Why iSWAB-RC-EL is the superior op...

READ MORE
Apr 11, 2023

Mawi DNA Announces Dr. Bouzyk as New Board Member!...

It is with great delight and excitement that we announce that Dr. READ MORE

Join our mailing list for updates and news about mawi

      • Our Product
      • FAQ
      • About Us
      • Contact
      • Resources
      • Blog

    Mawi DNA Technologies LLC

    1252 Quarry Lane Suite A,
    Pleasanton, CA | 94566

    Telephone: 510-256-5186

    Toll-Free: 855-DNA-SWAB

    LinkedinLinkedin TwitterTwitter YoutubeYoutube

    Copyright © 2023 Mawi DNA Technologies LLC.