iSWAB™-Discovery is a DNA collection kit for humans and animals that captures samples producing high yields of double stranded, long fragmented DNA from buccal cells using traditional swabs. Compared to the industry standards, the iSWAB™-DSC does not contain any alcohol, hazardous, or toxic ingredients and protects the integrity of DNA . The use of alcohol in sample collection can produce short DNA fragments, limiting their usability to basic genotyping applications.
Product Common Name: iSWAB™-DSC Bag
Product Full Name: iSWAB™-Discovery Human DNA Collection Device Bag
Part Number: ISF-T-DSC
Units: 400uL x 500 units
500 iSWAB™-DSC Devices
*The products shown contain the CE Mark and are approved for IVD use in countries recognizing this standard. In the USA, products are designated For Research Use Only and not for use in diagnostic procedures and will be labeled accordingly.
Population Genomics, Cancer research HLA typing, DNA sequencing; Sanger and Next generation sequencing, Epidemiology.
Each iSWAB™-DSC collection device consists of a collection tube that is pre-filled with 400 µL, respectively, of the nontoxic iSWAB™-DNA buffer and fitted with a proprietary insert. The insert is designed to optimize the release of specimens collected with swabs into the gentle lytic buffer, creating a minimal footprint and allowing for swab-free transport of specimens. Self-collection or assisted collection can be achieved in less than 5 minutes and is suitable for all population segments including infants, toddlers, and elderlies. iSWAB™-DSC is pre-barcoded for traceability and storage, and is easy to process via manual and automated applications. The device is human gDNA and PCR inhibitor free and collected samples are stable at room temperature (15-30 °C) for at least 60 days (Real Time).
The iSWAB™-DSC Collection device is a non-invasive and nontoxic sample collection technology for the collection, stabilization, concentration, transport, and storage of DNA samples. It is a swab-based sampling applicator and is intended to be used for sample collection of buccal cells. The DSC collection device for human use is designed to capture samples producing high yields of double-stranded, long fragmented DNA between 2-7μg with <3% bacterial contamination using traditional sampling swabs.
The iSWAB™-DSC collection device is intended for the collection of double-stranded, large fragment DNA at the point of collection without the need for swab inclusion. The gentle collection and lysis chemistry of the nontoxic iSWAB™-DSC buffer allows for recovery of DNA comparable to the genomic DNA generated from blood, making it suitable for complex genomics downstream assays such as microarrays, NGS, and Sanger sequencing. The device can be used for ambient temperature (15-30 °C) transport and storage. Ideal for: paternity testing, genealogy, ancestry, population genomics, cancer research, HLA typing, and epidemiology.
“Pre-collection: 3 years from date of manufacture between 15-30° C.
Transport temperature, post-collection: 15-30° C.
Sample stability and storage, post-collection: 60 days real time and 3 years accelerated time.If longer storage time is required, collected samples can be stored at -20 to -80° C.”
|# Swabs||# Swabs|
|Collection Volume||400 µl|
|Nucleic Acid Yield (μg)||2-7|
|Molecular Weight of DNA||>23 kb|
|Bacterial DNA content||<3%|
|Storage and Transport temperature||RT|
|Shelf Life Stability||3 years|
|Capability to concentrate sample||Yes|
|Suitable for all population segments||Yes|
|Applications||Population genomics, cancer research , epigenetics, and other genomic research|
|Compatible Extraction Methods||Investigator Quantiplex Kit (Qiagen, Cat. # 387016), Promega PowerpPlex 16 HS System (Promega, Cat. # DC2101), EZ1 Advanced XL DNA Investigator Flip-Cap Card (Qiagen, Cat. # 9019933),|
|Downstream Assays||WGS, NGS, Exome Sequencing, Sanger, Methylation, Telomere Length, TaqMan Open Array, Genotyping assays,|