Swab material should not be the limiting…
READ MORE
In a study published by the NPJ Genomic Medicine, Three young children presented with a neurodevelopmental disorder were studied to identify if there were pathogenic variants found in their ATG4D bi-allele. Instead of blood samples, oral DNA samples were collected from two of the three participants and…
READ MORE
Looking to Improve Your Success Rate Downstream for DNA Sequencing
When it comes to whole genome sequencing (WGS), customers are reporting a success rate of greater than 95% when utilizing Mawi DNA’s iSWAB-DNA sample collection devices. Here’s what’s different and why it matters. Bacterial DNA in WGS leads to reduced sequencing coverage, false positive variations, bias…
READ MORE
4 vs. 1 Achieve More With Less
Mawi’s iSWAB-DNA was used to collect saliva samples from parents and children for Whole Exome Sequencing. Two take away messages from this paper: We enable whole exome sequencing One iSWAB sample collection (iSWAB-DNA-250) vs. Four of DNA Genotek (OGR-175, OGR-500, OGR-525, and OGR-57) View Protocol
READ MORE
Appreciating Women in STEM
The month of March is National Women’s Month and Mawi DNA is celebrating the amazing women on our team that are bringing innovation to life. Our diverse team comes together everyday to push the boundaries of continuously innovating biosampling collection technology. At Mawi DNA the…
READ MOREAssociation of GREB1L Variants with Non-Syndromic Inner Ear Malformations
Here’s a research article about dnon-syndromic inner ear malformations and deafness that was written by Isabelle Schrauwen, Elina Kari, Jacob Mattox, Lorida Llaci, Joanna Smeeton, Marcus Naymik, David W. Raible, James A. Knowles, J. Gage Crump, Matthew J. Huentelman, Rick A. Friedman.
READ MOREDopaminergic Gene Methylation: Cognitive Performance in Twin Study
Here’s an research paper about dopaminergic gene methylation that was written by Candace R. Lewis ORCID Icon, Adrienne Henderson-Smith, Reagan S. Breitenstein ORCID Icon, Hayley A. Sowards, Ignazio S. Piras, Matthew J. Huentelman, Leah D. Doane & Kathryn Lemery-Chalfant.
READ MOREWhat is the difference between Non-Invasive vs Invasive Biosampling?
Painless No expertise needed No cold chain involvement Painful Requires expertise Handling infrastructure expensive (cold chain transport and storage)
READ MORENon-Invasive Pros and Cons
Traditional non-invasive sample collection has two approaches to try and collect and produce high gDNA recovery. While both methods have benefits, they also have their challenges. Self collection, but limited to individuals capable of producing sufficient saliva Collection solution contains alcohol Yields sheared, short-fragment DNA not optimal for…
READ MOREWhy Buccal Collection is Better Than Saliva/Spit Collection
Saliva Collection is not a Universal Sample Collection Tool: 20% - 46% of the Population Suffers from Dry Mouth Not everybody can produce enough saliva: Collecting 1-2 mL of Saliva within 30 minutes (as required by most saliva collection kits) can be very challenging for…
READ MOREEvaluation of TGFBI corneal dystrophy and molecular diagnostic testing
Here’s an review article about TGFBI corneal dystrophy that was written by Connie Chao-Shern, Lawrence A. DeDionisio, Jun-Heok Jang, Clara C. Chan, Vance Thompson, Kathleen Christie, M. Andrew Nesbit & C. B. Tara McMullen. In this paper they mention using the Mawi DNA iSWAB collection kit.
READ MORE
